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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM59A
All Species:
6.97
Human Site:
S569
Identified Species:
21.9
UniProt:
Q9H706
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H706
NP_073588.1
876
97186
S569
R
S
P
S
P
T
L
S
Y
Y
S
S
G
L
H
Chimpanzee
Pan troglodytes
XP_524002
932
103068
L625
T
R
S
P
S
P
T
L
S
Y
Y
S
S
G
L
Rhesus Macaque
Macaca mulatta
XP_001103392
618
69796
T329
R
A
V
R
D
V
K
T
D
W
N
E
D
C
K
Dog
Lupus familis
XP_547618
865
96077
L558
T
R
S
P
S
P
T
L
S
Y
Y
S
S
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3UFT3
876
97249
L568
T
R
S
P
S
P
T
L
S
Y
Y
S
S
G
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509268
641
69426
T352
S
L
Y
C
Y
P
C
T
W
G
D
C
K
V
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NRE4
876
97412
S568
R
S
P
S
P
T
L
S
Y
Y
S
S
G
L
H
Zebra Danio
Brachydanio rerio
Q7ZVU1
867
95774
K561
T
V
P
Y
P
S
A
K
P
R
Q
K
D
T
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.8
62.6
90.4
N.A.
91.3
N.A.
N.A.
32.6
N.A.
78
63.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
93.4
66
93.2
N.A.
95
N.A.
N.A.
45.4
N.A.
85.3
73.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
6.6
13.3
N.A.
13.3
N.A.
N.A.
0
N.A.
100
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
33.3
13.3
N.A.
13.3
N.A.
N.A.
20
N.A.
100
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
0
0
0
0
13
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
13
0
0
13
0
0
0
0
13
0
13
0
% C
% Asp:
0
0
0
0
13
0
0
0
13
0
13
0
25
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
13
0
0
25
38
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
13
13
0
0
0
13
13
0
13
% K
% Leu:
0
13
0
0
0
0
25
38
0
0
0
0
0
25
38
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% N
% Pro:
0
0
38
38
38
50
0
0
13
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% Q
% Arg:
38
38
0
13
0
0
0
0
0
13
0
0
0
0
13
% R
% Ser:
13
25
38
25
38
13
0
25
38
0
25
63
38
0
0
% S
% Thr:
50
0
0
0
0
25
38
25
0
0
0
0
0
13
0
% T
% Val:
0
13
13
0
0
13
0
0
0
0
0
0
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
13
13
0
0
0
0
0
% W
% Tyr:
0
0
13
13
13
0
0
0
25
63
38
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _